Name: Sensius
Address: nl

Professionals

We developed the next generation hyperthermia system to support solid cancer treatments

Localized heating is generated by an integrated system of microwave sources controlled by interactive software. The treatment is completely reproducible. The workflow is aligned to radiotherapy, which makes adoption easy. We term this thermotherapy.

By heating a tumour to 42⁰C the regular therapy is enhanced. This creates the option to either escalate the clinical outcome, or to lower the traditional treatment’s dose and thus lower toxicity, adding Quality of Life for the patient.

Evidence suggests adding thermotherapy can reduce radiotherapy dose by 4-10Gy¹.

The interactive software allows the therapist to make adjustments during treatment based on feedback from sensors and the patient. This adaptive treatment enables the therapist to interact with patients to improve the Quality of Life achieved.

The basis for the high performance lies in the use of a high frequency (434 MHz), the high number of microwave sources (20), the water bolus, the segmentation software and the interactivity whereby the patient is involved in real time.

¹ HP Kok, TD Herrera, JC Crezee; The relevance of high temperatures and short time intervals between radiation therapy and hyperthermia: insights in terms of predicted equivalent enhanced radiation dose; Radiation oncology, Oct 2022

The Steps: Workflow of a Head and Neck Hyperthermia Treatment: designed to be integrated.

In our system we are able to act upon feedback by the patient.

The process consists of five consecutive steps:

patient scanning (MRI or CT);
3D model generation;
treatment set-up optimization;
simulation & optimization;
actual treatment of the patient.

Simulation guided H&N hyperthermia

Our software allows the therapist to make adjustments during treatment based on feedback from sensors and the patient.

The patient contributes in optimising the treatment giving feedback on toxicity. This adaptive treatment enables the therapist to interact with patients to perfectly balance treatment efficacy while keeping toxicity to a minimum. We termed this cooperation between therapist, patient and interactive adaptation a balanced treatment.